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I-TASSER

Threading-based modelling with function and ligand-site prediction.

Server

I-TASSER

Zhang Lab · zhanggroup.org

Does
Threading-based modelling with function and ligand-site prediction.
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Sign-in
Licence
Academic use; commercial licence required
Limits
Server queue, often hours to days

Use this when

You want function and binding-site prediction alongside a model, not just coordinates. For raw structural accuracy the AlphaFold family has overtaken it, and returns results in minutes rather than days.

Open I-TASSER

External tool. We link, we don’t host — nothing you enter on Biology 101 reaches them.

About this tool

Builds models by threading against known folds, and reports predicted function, ligand binding sites and GO terms alongside the structure.

Science last reviewed .